Targeting the ubiquitination/deubiquitination process to regulate immune checkpoint pathways
نویسندگان
چکیده
منابع مشابه
Targeting immune checkpoint pathways overcomes tumor-induced CD8+ T cell suppression
The immune system has the potential to be a powerful tool to destroy tumors. However despite ample evidence of anti-tumor immune responses in many patients, as well as years of immunotherapy development, truly effective immune-based therapies remain out of reach. We have previously shown that short-term in vitro co-culture of human T cells with human-derived tumor cell lines of various origins ...
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ژورنال
عنوان ژورنال: Signal Transduction and Targeted Therapy
سال: 2021
ISSN: 2059-3635
DOI: 10.1038/s41392-020-00418-x